Inference of microRNA transfection via target gene expression

• Item type: SIG Technical Reports(1)
• 公開日: 2010-06-11
• タイトル: Inference of microRNA transfection via target gene expression
• タイトル / 言語: en
• タイトル: Inference of microRNA transfection via target gene expression
• 言語: eng
• 資源タイプ / 資源タイプ識別子: http://purl.org/coar/resource_type/c_18gh
• 資源タイプ: technical report
• 著者所属: Department of Physics, Chuo University, Tokyo, Japan
• 著者所属: COE Fellow, Graduate School of Medicine, Tohoku University, Sendai, Japan／Presently with Department of Cell Biology, The JFCR-Cancer Institute, Tokyo, Japan
• 著者所属(英): en
• 著者所属(英): Department of Physics, Chuo University, Tokyo, Japan
• 著者所属(英): en
• 著者所属(英): COE Fellow, Graduate School of Medicine, Tohoku University, Sendai, Japan / Presently with Department of Cell Biology, The JFCR-Cancer Institute, Tokyo, Japan
• 著者名: Y-h.Taguchi; Jun, Yasuda
• 著者名(英): Y-h., Taguchi; Jun, Yasuda
• 論文抄録 / 内容記述タイプ: Other
• 論文抄録 / 内容記述: MicroRNA (miRNA) is a new candidate to regulate gene expression in epigenetic manners. It turns out that each can really regulate expression of hundreds of genes in the manner dependent upon several situations, e.g., developmental stages, deceases, and external conditions. In spite of that, how and when miRNAs can regulate target genes' expression and what target genes are is unclear. In this paper, we have investigated regulation of gene expression via miRNA transfection, by using both gene expression profile and computationally predicted target genes. The miRNA, let-7a, transfected to tumors was listed at the top most plausible candidate by this analysis.
• 論文抄録(英) / 内容記述タイプ: Other
• 論文抄録(英) / 内容記述: MicroRNA (miRNA) is a new candidate to regulate gene expression in epigenetic manners. It turns out that each can really regulate expression of hundreds of genes in the manner dependent upon several situations, e.g., developmental stages, deceases, and external conditions. In spite of that, how and when miRNAs can regulate target genes' expression and what target genes are is unclear. In this paper, we have investigated regulation of gene expression via miRNA transfection, by using both gene expression profile and computationally predicted target genes. The miRNA, let-7a, transfected to tumors was listed at the top most plausible candidate by this analysis.
• 書誌レコードID / 収録物識別子タイプ: NCID
• 書誌レコードID / 収録物識別子: AA12055912
• 書誌情報: 研究報告バイオ情報学（BIO）; 巻 2010-BIO-21, 号 6, p. 1-6, 発行日 2010-06-11
• Notice: SIG Technical Reports are nonrefereed and hence may later appear in any journals, conferences, symposia, etc.
• 出版者 / 言語: ja
• 出版者: 情報処理学会