{"created":"2025-01-19T01:45:55.792666+00:00","updated":"2025-01-19T07:41:34.800935+00:00","metadata":{"_oai":{"id":"oai:ipsj.ixsq.nii.ac.jp:00241333","sets":["1164:5352:11553:11808"]},"path":["11808"],"owner":"44499","recid":"241333","title":["拡散モデルを用いたRNA配列および二次構造の同時生成"],"pubdate":{"attribute_name":"公開日","attribute_value":"2024-11-27"},"_buckets":{"deposit":"706fc359-b7e4-4fb6-898a-14d8f82af5f7"},"_deposit":{"id":"241333","pid":{"type":"depid","value":"241333","revision_id":0},"owners":[44499],"status":"published","created_by":44499},"item_title":"拡散モデルを用いたRNA配列および二次構造の同時生成","author_link":["664138","664139"],"item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"拡散モデルを用いたRNA配列および二次構造の同時生成"}]},"item_type_id":"4","publish_date":"2024-11-27","item_4_text_3":{"attribute_name":"著者所属","attribute_value_mlt":[{"subitem_text_value":"早稲田大学"},{"subitem_text_value":"早稲田大学／産業技術総合研究所／日本医科大学"}]},"item_4_text_4":{"attribute_name":"著者所属(英)","attribute_value_mlt":[{"subitem_text_value":"Waseda University","subitem_text_language":"en"},{"subitem_text_value":"Waseda University / National Institute of Advanced Industrial Science and Technology / Nippon Medical School","subitem_text_language":"en"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_publisher":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"情報処理学会","subitem_publisher_language":"ja"}]},"publish_status":"0","weko_shared_id":-1,"item_file_price":{"attribute_name":"Billing file","attribute_type":"file","attribute_value_mlt":[{"url":{"url":"https://ipsj.ixsq.nii.ac.jp/record/241333/files/IPSJ-BIO24080005.pdf","label":"IPSJ-BIO24080005.pdf"},"date":[{"dateType":"Available","dateValue":"2026-11-27"}],"format":"application/pdf","billing":["billing_file"],"filename":"IPSJ-BIO24080005.pdf","filesize":[{"value":"1.4 MB"}],"mimetype":"application/pdf","priceinfo":[{"tax":["include_tax"],"price":"660","billingrole":"5"},{"tax":["include_tax"],"price":"330","billingrole":"6"},{"tax":["include_tax"],"price":"0","billingrole":"41"},{"tax":["include_tax"],"price":"0","billingrole":"44"}],"accessrole":"open_date","version_id":"db448248-3985-4331-a5bb-94412cb0e7c1","displaytype":"detail","licensetype":"license_note","license_note":"Copyright (c) 2024 by the Information Processing Society of Japan"}]},"item_4_creator_5":{"attribute_name":"著者名","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"中野, 涼太"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"浜田, 道昭"}],"nameIdentifiers":[{}]}]},"item_4_source_id_9":{"attribute_name":"書誌レコードID","attribute_value_mlt":[{"subitem_source_identifier":"AA12055912","subitem_source_identifier_type":"NCID"}]},"item_4_textarea_12":{"attribute_name":"Notice","attribute_value_mlt":[{"subitem_textarea_value":"SIG Technical Reports are nonrefereed and hence may later appear in any journals, conferences, symposia, etc."}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourceuri":"http://purl.org/coar/resource_type/c_18gh","resourcetype":"technical report"}]},"item_4_source_id_11":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"2188-8590","subitem_source_identifier_type":"ISSN"}]},"item_4_description_7":{"attribute_name":"論文抄録","attribute_value_mlt":[{"subitem_description":"核酸医薬品の事業活性化に伴い，RNA 創薬の候補分子生成ツールとしての生成モデルの確立が急がれている．しかし従来の RNA 生成モデルは主に配列に焦点を当てており，RNA の機能発現に重要な影響を与えるとされる構造情報への配慮が欠けているものが多い．本研究では RNA の構造表現としてロバストとされている二次構造を潜在変数モデルに組み込み，離散拡散モデル D3PM の概念を拡張し配列・構造同時生成モデルを構築した．本手法は配列と構造の分布を同時に測るメトリクスにおいて従来手法の性能と同じかそれ以上の性能を打ち出しており，条件付け生成や潜在空間化など，将来的に幅広く応用されることが期待されている．","subitem_description_type":"Other"}]},"item_4_biblio_info_10":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicPageEnd":"4","bibliographic_titles":[{"bibliographic_title":"研究報告バイオ情報学（BIO）"}],"bibliographicPageStart":"1","bibliographicIssueDates":{"bibliographicIssueDate":"2024-11-27","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"5","bibliographicVolumeNumber":"2024-BIO-80"}]},"relation_version_is_last":true,"weko_creator_id":"44499"},"id":241333,"links":{}}