Anomalous US-wide prevalence of reversion mutants in the emergence of Omicron BA.1

• Item type: SIG Technical Reports(1)
• 公開日: 2024-08-30
• タイトル: Anomalous US-wide prevalence of reversion mutants in the emergence of Omicron BA.1
• タイトル / 言語: en
• タイトル: Anomalous US-wide prevalence of reversion mutants in the emergence of Omicron BA.1
• 言語: eng
• 資源タイプ / 資源タイプ識別子: http://purl.org/coar/resource_type/c_18gh
• 資源タイプ: technical report
• 著者所属: University of Tsukuba
• 著者所属(英): en
• 著者所属(英): University of Tsukuba
• 著者名: Hideki, Kakeya
• 著者名(英): Hideki, Kakeya
• 論文抄録 / 内容記述タイプ: Other
• 論文抄録 / 内容記述: Surface glycoprotein sequences of the Omicron BA.1 lineage that include only reverse mutations were searched in NCBI GenBank, where the dates and the locations of collection were retrieved for each mutant. Data from BA.1.x lineages that appeared during the same period of time were used as a control, and the early spread of these mutants were compared. The number of states where the first 20 samples were found was compared between the group of reversion mutants and the control group. The result shows that the reversion mutants were widespread from the early days of their emergence, which shows statistically significant differences compared to the control group. The wide prevalence of reversion mutants of BA.1 from the beginning of their emergence is highly anomalous and extremely unlikely to occur without human intervention.
• 論文抄録(英) / 内容記述タイプ: Other
• 論文抄録(英) / 内容記述: Surface glycoprotein sequences of the Omicron BA.1 lineage that include only reverse mutations were searched in NCBI GenBank, where the dates and the locations of collection were retrieved for each mutant. Data from BA.1.x lineages that appeared during the same period of time were used as a control, and the early spread of these mutants were compared. The number of states where the first 20 samples were found was compared between the group of reversion mutants and the control group. The result shows that the reversion mutants were widespread from the early days of their emergence, which shows statistically significant differences compared to the control group. The wide prevalence of reversion mutants of BA.1 from the beginning of their emergence is highly anomalous and extremely unlikely to occur without human intervention.
• 書誌レコードID / 収録物識別子タイプ: NCID
• 書誌レコードID / 収録物識別子: AA12055912
• 書誌情報: 研究報告バイオ情報学（BIO）; 巻 2024-BIO-79, 号 2, p. 1-6, 発行日 2024-08-30
• ISSN / 収録物識別子タイプ: ISSN
• ISSN / 収録物識別子: 2188-8590
• Notice: SIG Technical Reports are nonrefereed and hence may later appear in any journals, conferences, symposia, etc.
• 出版者 / 言語: ja
• 出版者: 情報処理学会