{"metadata":{"_oai":{"id":"oai:ipsj.ixsq.nii.ac.jp:00236768","sets":["6504:11678:11684"]},"path":["11684"],"owner":"44499","recid":"236768","title":["臨床応用を見据えた遺伝子変異の病的意義判定AIの開発"],"pubdate":{"attribute_name":"公開日","attribute_value":"2024-03-01"},"_buckets":{"deposit":"b77583b0-379a-41b3-ae24-33d6d78d89d7"},"_deposit":{"id":"236768","pid":{"type":"depid","value":"236768","revision_id":0},"owners":[44499],"status":"published","created_by":44499},"item_title":"臨床応用を見据えた遺伝子変異の病的意義判定AIの開発","author_link":["647363","647367","647370","647371","647365","647368","647369","647366","647364"],"item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"臨床応用を見据えた遺伝子変異の病的意義判定AIの開発"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"コンピュータと人間社会","subitem_subject_scheme":"Other"}]},"item_type_id":"22","publish_date":"2024-03-01","item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_22_text_3":{"attribute_name":"著者所属","attribute_value_mlt":[{"subitem_text_value":"日立"},{"subitem_text_value":"日立"},{"subitem_text_value":"国立がん研究センター 中央病院"},{"subitem_text_value":"国立がん研究センター 中央病院"},{"subitem_text_value":"国立がん研究センター 中央病院"},{"subitem_text_value":"国立がん研究センター 中央病院"},{"subitem_text_value":"国立がん研究センター 中央病院"},{"subitem_text_value":"国立がん研究センター 研究所"},{"subitem_text_value":"国立がん研究センター 研究所"}]},"item_publisher":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"情報処理学会","subitem_publisher_language":"ja"}]},"publish_status":"0","weko_shared_id":-1,"item_file_price":{"attribute_name":"Billing file","attribute_type":"file","attribute_value_mlt":[{"url":{"url":"https://ipsj.ixsq.nii.ac.jp/record/236768/files/IPSJ-Z86-5G-02.pdf","label":"IPSJ-Z86-5G-02.pdf"},"date":[{"dateType":"Available","dateValue":"2024-07-04"}],"format":"application/pdf","filename":"IPSJ-Z86-5G-02.pdf","filesize":[{"value":"472.3 kB"}],"mimetype":"application/pdf","accessrole":"open_date","version_id":"3393be34-36cc-489c-aa19-2bfd0c7467e7","displaytype":"detail","licensetype":"license_note","license_note":"Copyright (c) 2024 by the Information Processing Society of Japan"}]},"item_22_creator_5":{"attribute_name":"著者名","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"阿部, 祥歩"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"安田, 知弘"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"小山, 隆文"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"角南, 久仁子"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"久保, 崇"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"平田, 真"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"須藤, 一起"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"田尾, 佳代子"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"浜本, 隆二"}],"nameIdentifiers":[{}]}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourceuri":"http://purl.org/coar/resource_type/c_5794","resourcetype":"conference paper"}]},"item_22_source_id_9":{"attribute_name":"書誌レコードID","attribute_value_mlt":[{"subitem_source_identifier":"AN00349328","subitem_source_identifier_type":"NCID"}]},"item_22_description_7":{"attribute_name":"論文抄録","attribute_value_mlt":[{"subitem_description":"がんパネル検査結果の解釈における専門家の負担軽減のため、遺伝子変異の病的意義判定AIへの期待が高まっている。しかし、AIにより変異の病的意義が判定された場合、最終的には判定に対し専門家による妥当性確認が必要なため、依然として専門家の負担が大きい。そこで我々は、専門家による病的意義判定結果を学習データとし公開データベース等に基づき変異の病的意義を推測するAIを開発している一方で、専門家による妥当性確認の負担軽減のため各変異に対してエビデンスの充実度に関するスコアも推定・提示し、エビデンスが十分かつ判断の難しい専門家が特に議論すべき変異を提示する技術も開発しており、それらについて報告する。","subitem_description_type":"Other"}]},"item_22_biblio_info_10":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicPageEnd":"312","bibliographic_titles":[{"bibliographic_title":"第86回全国大会講演論文集"}],"bibliographicPageStart":"311","bibliographicIssueDates":{"bibliographicIssueDate":"2024-03-01","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"1","bibliographicVolumeNumber":"2024"}]},"relation_version_is_last":true,"weko_creator_id":"44499"},"id":236768,"updated":"2025-01-19T09:07:50.839701+00:00","links":{},"created":"2025-01-19T01:39:00.620887+00:00"}