{"metadata":{"_oai":{"id":"oai:ipsj.ixsq.nii.ac.jp:00232794","sets":["1164:2735:11468:11517"]},"path":["11517"],"owner":"44499","recid":"232794","title":["TDbasedUFEを用いた黄色ブドウ球菌敗血症におけるメチシリン耐性の解析"],"pubdate":{"attribute_name":"公開日","attribute_value":"2024-02-29"},"_buckets":{"deposit":"b83e17ae-67ca-48bd-a527-c9fe0decd898"},"_deposit":{"id":"232794","pid":{"type":"depid","value":"232794","revision_id":0},"owners":[44499],"status":"published","created_by":44499},"item_title":"TDbasedUFEを用いた黄色ブドウ球菌敗血症におけるメチシリン耐性の解析","author_link":["631022","631023"],"item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"TDbasedUFEを用いた黄色ブドウ球菌敗血症におけるメチシリン耐性の解析"},{"subitem_title":"Analysis of Methicillin Resistance in <i>Staphylococcus Aureus</i> Sepsis Using TDbasedUFE","subitem_title_language":"en"}]},"item_type_id":"4","publish_date":"2024-02-29","item_4_text_3":{"attribute_name":"著者所属","attribute_value_mlt":[{"subitem_text_value":"中央大学理工学部物理学科"},{"subitem_text_value":"中央大学理工学部物理学科"}]},"item_4_text_4":{"attribute_name":"著者所属(英)","attribute_value_mlt":[{"subitem_text_value":"Department of Physics, Chuo University","subitem_text_language":"en"},{"subitem_text_value":"Department of Physics, Chuo University","subitem_text_language":"en"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_publisher":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"情報処理学会","subitem_publisher_language":"ja"}]},"publish_status":"0","weko_shared_id":-1,"item_file_price":{"attribute_name":"Billing file","attribute_type":"file","attribute_value_mlt":[{"url":{"url":"https://ipsj.ixsq.nii.ac.jp/record/232794/files/IPSJ-MPS24147011.pdf","label":"IPSJ-MPS24147011.pdf"},"date":[{"dateType":"Available","dateValue":"2026-03-01"}],"format":"application/pdf","billing":["billing_file"],"filename":"IPSJ-MPS24147011.pdf","filesize":[{"value":"1.8 MB"}],"mimetype":"application/pdf","priceinfo":[{"tax":["include_tax"],"price":"660","billingrole":"5"},{"tax":["include_tax"],"price":"330","billingrole":"6"},{"tax":["include_tax"],"price":"0","billingrole":"17"},{"tax":["include_tax"],"price":"0","billingrole":"44"}],"accessrole":"open_date","version_id":"dc8019cf-4f2e-458c-bee8-c8d12cdd37de","displaytype":"detail","licensetype":"license_note","license_note":"Copyright (c) 2024 by the Information Processing Society of Japan"}]},"item_4_creator_5":{"attribute_name":"著者名","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"渡邉, 将太郎"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"田口, 善弘"}],"nameIdentifiers":[{}]}]},"item_4_source_id_9":{"attribute_name":"書誌レコードID","attribute_value_mlt":[{"subitem_source_identifier":"AN10505667","subitem_source_identifier_type":"NCID"}]},"item_4_textarea_12":{"attribute_name":"Notice","attribute_value_mlt":[{"subitem_textarea_value":"SIG Technical Reports are nonrefereed and hence may later appear in any journals, conferences, symposia, etc."}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourceuri":"http://purl.org/coar/resource_type/c_18gh","resourcetype":"technical report"}]},"item_4_source_id_11":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"2188-8833","subitem_source_identifier_type":"ISSN"}]},"item_4_description_7":{"attribute_name":"論文抄録","attribute_value_mlt":[{"subitem_description":"scATAC-seq はクロマチンアクセシビリティを細胞の解像度をもって明らかにし，臨床における病理学や病態を理解するうえで重要である．しかしながら scATAC-seq のデータは疎らかつ巨大であるため，それらの多次元的な解析は困難である．TDbasedUFE は複数の条件下で教師なし分類が可能であるため，scATAC-seq の解析に適している．我々は TDbasedUFE を用いて，黄色ブドウ球菌による敗血症患者の末梢血単核細胞（PBMC）の scATAC-seq のデータの分析を行った．本研究では敗血症におけるメチシリン耐性黄色ブドウ球菌（MRSA）とメチシリン感化黄色ブドウ球菌（MSSA）感染の間で，異なる応答を示す遺伝子を細胞の種類ごとに抽出し，その機能を予測した．これらの結果は TDbasedUFE が scATAC-seq のデータの解析に適していることを実証した．","subitem_description_type":"Other"}]},"item_4_biblio_info_10":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicPageEnd":"6","bibliographic_titles":[{"bibliographic_title":"研究報告数理モデル化と問題解決（MPS）"}],"bibliographicPageStart":"1","bibliographicIssueDates":{"bibliographicIssueDate":"2024-02-29","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"11","bibliographicVolumeNumber":"2024-MPS-147"}]},"relation_version_is_last":true,"weko_creator_id":"44499"},"id":232794,"updated":"2025-01-19T10:19:10.351790+00:00","links":{},"created":"2025-01-19T01:33:51.985944+00:00"}