{"metadata":{"_oai":{"id":"oai:ipsj.ixsq.nii.ac.jp:00215560","sets":["6504:10735:10811"]},"path":["10811"],"owner":"44499","recid":"215560","title":["糖鎖情報を組み込んだニューラルネットワークによる薬剤とタンパク質の相互作用予測"],"pubdate":{"attribute_name":"公開日","attribute_value":"2021-03-04"},"_buckets":{"deposit":"fb392219-eb19-45b9-a7ff-9600cf67f318"},"_deposit":{"id":"215560","pid":{"type":"depid","value":"215560","revision_id":0},"owners":[44499],"status":"published","created_by":44499},"item_title":"糖鎖情報を組み込んだニューラルネットワークによる薬剤とタンパク質の相互作用予測","author_link":["555064","555060","555058","555063","555062","555061","555059"],"item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"糖鎖情報を組み込んだニューラルネットワークによる薬剤とタンパク質の相互作用予測"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"コンピュータと人間社会","subitem_subject_scheme":"Other"}]},"item_type_id":"22","publish_date":"2021-03-04","item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_22_text_3":{"attribute_name":"著者所属","attribute_value_mlt":[{"subitem_text_value":"創価大"},{"subitem_text_value":"創価大"},{"subitem_text_value":"創価大"},{"subitem_text_value":"創価大"},{"subitem_text_value":"創価大"},{"subitem_text_value":"創価大"},{"subitem_text_value":"創価大"}]},"item_publisher":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"情報処理学会","subitem_publisher_language":"ja"}]},"publish_status":"0","weko_shared_id":-1,"item_file_price":{"attribute_name":"Billing file","attribute_type":"file","attribute_value_mlt":[{"url":{"url":"https://ipsj.ixsq.nii.ac.jp/record/215560/files/IPSJ-Z83-4ZC-02.pdf","label":"IPSJ-Z83-4ZC-02.pdf"},"date":[{"dateType":"Available","dateValue":"2021-12-29"}],"format":"application/pdf","filename":"IPSJ-Z83-4ZC-02.pdf","filesize":[{"value":"425.2 kB"}],"mimetype":"application/pdf","accessrole":"open_date","version_id":"2553f74f-20c4-4fec-8383-3016b3f88a78","displaytype":"detail","licensetype":"license_note","license_note":"Copyright (c) 2021 by the Information Processing Society of Japan"}]},"item_22_creator_5":{"attribute_name":"著者名","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"新川, 栄二"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"村田, 祐樹"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"永塚, 光一"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"小野, 多美子"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"細田, 正恵"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"木下, 聖子"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"渥美, 雅保"}],"nameIdentifiers":[{}]}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourceuri":"http://purl.org/coar/resource_type/c_5794","resourcetype":"conference paper"}]},"item_22_source_id_9":{"attribute_name":"書誌レコードID","attribute_value_mlt":[{"subitem_source_identifier":"AN00349328","subitem_source_identifier_type":"NCID"}]},"item_22_description_7":{"attribute_name":"論文抄録","attribute_value_mlt":[{"subitem_description":"近年，医薬データ等の増加に伴い創薬分野における機械学習を用いた研究が盛んに行われている．特に標的物質と薬剤の相互作用を予測することは既存薬剤の新規効能を発見するドラッグリポジショニングにのみならず，その相互作用部位を解析することで新薬開発においても有用である．本研究では，第三の生命鎖として注目されている糖鎖に着目し，薬剤と糖タンパク質の相互作用予測において，(1)薬剤，アミノ酸配列情報，(2)薬剤，糖鎖情報，(3)薬剤，アミノ酸配列情報，糖鎖情報の3つの組み合わせを入力とするニューラルネットワークモデルを構築した．実験結果より，糖鎖情報を用いた(2)と(3)において(1)よりも高い予測性能が得られた．","subitem_description_type":"Other"}]},"item_22_biblio_info_10":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicPageEnd":"470","bibliographic_titles":[{"bibliographic_title":"第83回全国大会講演論文集"}],"bibliographicPageStart":"469","bibliographicIssueDates":{"bibliographicIssueDate":"2021-03-04","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"1","bibliographicVolumeNumber":"2021"}]},"relation_version_is_last":true,"weko_creator_id":"44499"},"id":215560,"updated":"2025-01-19T16:06:14.253945+00:00","links":{},"created":"2025-01-19T01:16:19.557505+00:00"}