{"id":209961,"metadata":{"_oai":{"id":"oai:ipsj.ixsq.nii.ac.jp:00209961","sets":["1164:5352:10544:10545"]},"path":["10545"],"owner":"44499","recid":"209961","title":["同期性揺らぎ遺伝子の二段階抽出におけるパラメータ調整法"],"pubdate":{"attribute_name":"公開日","attribute_value":"2021-03-04"},"_buckets":{"deposit":"15f1a95f-b1d0-474c-b218-c504b9f4d237"},"_deposit":{"id":"209961","pid":{"type":"depid","value":"209961","revision_id":0},"owners":[44499],"status":"published","created_by":44499},"item_title":"同期性揺らぎ遺伝子の二段階抽出におけるパラメータ調整法","author_link":["530607","530608"],"item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"同期性揺らぎ遺伝子の二段階抽出におけるパラメータ調整法"},{"subitem_title":"Parameter adjustment method in two-step extraction of synchronously fluctuated genes","subitem_title_language":"en"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":" 一般発表","subitem_subject_scheme":"Other"}]},"item_type_id":"4","publish_date":"2021-03-04","item_4_text_3":{"attribute_name":"著者所属","attribute_value_mlt":[{"subitem_text_value":"富山大学和漢医薬学総合研究所"}]},"item_4_text_4":{"attribute_name":"著者所属(英)","attribute_value_mlt":[{"subitem_text_value":"Institute of Natural Medicine, University of Toyama","subitem_text_language":"en"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_publisher":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"情報処理学会","subitem_publisher_language":"ja"}]},"publish_status":"0","weko_shared_id":-1,"item_file_price":{"attribute_name":"Billing file","attribute_type":"file","attribute_value_mlt":[{"url":{"url":"https://ipsj.ixsq.nii.ac.jp/record/209961/files/IPSJ-BIO21065005.pdf","label":"IPSJ-BIO21065005.pdf"},"date":[{"dateType":"Available","dateValue":"2023-03-04"}],"format":"application/pdf","billing":["billing_file"],"filename":"IPSJ-BIO21065005.pdf","filesize":[{"value":"465.4 kB"}],"mimetype":"application/pdf","priceinfo":[{"tax":["include_tax"],"price":"660","billingrole":"5"},{"tax":["include_tax"],"price":"330","billingrole":"6"},{"tax":["include_tax"],"price":"0","billingrole":"41"},{"tax":["include_tax"],"price":"0","billingrole":"44"}],"accessrole":"open_date","version_id":"e07b8d82-59ce-4214-8bf1-9ac70061180f","displaytype":"detail","licensetype":"license_note","license_note":"Copyright (c) 2021 by the Information Processing Society of Japan"}]},"item_4_creator_5":{"attribute_name":"著者名","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"奥, 牧人"}],"nameIdentifiers":[{}]}]},"item_4_creator_6":{"attribute_name":"著者名(英)","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"Makito, Oku","creatorNameLang":"en"}],"nameIdentifiers":[{}]}]},"item_4_source_id_9":{"attribute_name":"書誌レコードID","attribute_value_mlt":[{"subitem_source_identifier":"AA12055912","subitem_source_identifier_type":"NCID"}]},"item_4_textarea_12":{"attribute_name":"Notice","attribute_value_mlt":[{"subitem_textarea_value":"SIG Technical Reports are nonrefereed and hence may later appear in any journals, conferences, symposia, etc."}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourceuri":"http://purl.org/coar/resource_type/c_18gh","resourcetype":"technical report"}]},"item_4_source_id_11":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"2188-8590","subitem_source_identifier_type":"ISSN"}]},"item_4_description_7":{"attribute_name":"論文抄録","attribute_value_mlt":[{"subitem_description":"同期性揺らぎ遺伝子とは特定の条件下で発現量が同期的に大きく揺らぐ遺伝子集合のことである．それらは生体の恒常性維持機能の低下と関係している可能性がある．同期性揺らぎ遺伝子の二段階抽出では，まず揺らぎの大きな遺伝子を選択し，次にその中から同期性遺伝子クラスタを抽出する．この二段階法は 2 つの重要なパラメータを持つが，それらの調整の仕方は確立されていなかった．この問題に対処するために，本稿では，同期性揺らぎ遺伝子の二段階抽出におけるパラメータ調整法を提案する．提案手法は，パラメータを先行研究で使用していた値に固定した場合と比べて，様々な条件下における試行の 77% で人工データに対する抽出性能を改善した．また，提案手法はパラメータ固定の場合と同様に実データに対する中程度の再現性を示した．","subitem_description_type":"Other"}]},"item_4_description_8":{"attribute_name":"論文抄録(英)","attribute_value_mlt":[{"subitem_description":"Synchronously fluctuated genes (SFGs) are a set of genes whose expressions fluctuate largely and synchronously under certain conditions. They may be associated with reduced homeostasis of living organisms. In the two-step extraction of SFGs, the genes with large fluctuations are selected first, and then synchronous gene clusters are extracted from them. The two-step method has two important parameters, but no method has been established to adjust them. In order to address this issue, in this paper, I propose a parameter adjustment method in two-step extraction of SFGs. The proposed method improved extraction performance for artificial data in 77 % of trials under various conditions, as compared to the case where the parameters were fixed at the values used in the previous study. In addition, the proposed method showed a moderate level of reproducibility for the real data as in the case of fixed parameters.","subitem_description_type":"Other"}]},"item_4_biblio_info_10":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicPageEnd":"6","bibliographic_titles":[{"bibliographic_title":"研究報告バイオ情報学（BIO）"}],"bibliographicPageStart":"1","bibliographicIssueDates":{"bibliographicIssueDate":"2021-03-04","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"5","bibliographicVolumeNumber":"2021-BIO-65"}]},"relation_version_is_last":true,"weko_creator_id":"44499"},"updated":"2025-01-19T18:19:41.241164+00:00","created":"2025-01-19T01:11:14.366793+00:00","links":{}}