@article{oai:ipsj.ixsq.nii.ac.jp:00206694,
 author = {杉本, 健太郎 and 小池, 千尋 and 森本, 高子 and 青西, 亨 and Kentaro, Sugimoto and Chihiro, Koike and Takako, Morimoto and Toru, Aonishi},
 issue = {2},
 journal = {情報処理学会論文誌数理モデル化と応用（TOM）},
 month = {Aug},
 note = {Waterfall illusionとは，一定方向に回転する刺激をしばらく見続けた後に刺激が停止すると，刺激が動いていたときとは逆方向に動いてみえるという錯視である．SrinivasanとDvorakは，実験によりハエがWaterfall illusionを知覚する可能性を示し，さらに，視葉内の動き検知細胞においてその知覚と相関したリバウンド応答および抑制性応答を報告している．これを受け，本研究ではハエのWaterfall illusionの知覚が，視葉内の動き検知細胞の一種であるLobula plate tangential cells（LPTCs）が構成するネットワークに起因すると仮説を立てた．そして，T型カルシウムチャネルを導入したLPTCsの回路モデルを構築し，この特徴的な膜電位応答の再現を試みた．その結果，刺激停止後での特徴的な膜電位応答であるリバウンド応答および抑制性応答を再現できた．本モデルから，T型カルシウムチャネルはリバウンド応答のトリガーの役割を果たし，LPTCs回路が反響回路として動作してリバウンド応答を促進することが示された．また，抑制性応答はリバウンド応答した細胞からの抑制により生じうることが示された．これらの結果は，ハエのWaterfall illusionの知覚の背後にある神経基盤の可能性の1つを示すものである．, Waterfall illusion is a motion aftereffect experienced when looking at a stationary stimulus after watching a stimulus moving in one direction for some time. The stationary stimulus appears to have movement in the opposite direction to the moving stimulus previously exposed. Srinivasan and Dvorak suggested the possibility that the fly could perceive the waterfall illusion, and its motion-sensitive neurons might induce rebound and inhibitory responses correlated with this perception. In this paper, we hypothesized that this perception is based on a network consisting of Lobula plate tangential cells (LPTCs), which were ones of motion-sensitive neurons. To test the hypothesis, we constructed a circuit model of LPTCs getting the newly introduced T-type calcium channel, and tried to reproduce this characteristic neural response after the stimulation was stopped. As a result of numerical simulation using the circuit model of LPTCs, we were able to reproduce the rebound and inhibitory responses. The result of simulation suggested that T-type calcium channel could act as a trigger for the rebound response, and LPTCs circuit might work as a reverberation circuit to promote the rebound response. This result also showed that the inhibitory response could be caused by suppression from the cells inducing the rebound response. In conclusion, this study showed one of the possible neural mechanisms underlying fly's waterfall illusion.},
 pages = {10--21},
 title = {ハエ動き検知神経回路モデルによるWaterfall illusionの機序理解},
 volume = {13},
 year = {2020}
}