{"links":{},"id":2002710,"metadata":{"_oai":{"id":"oai:ipsj.ixsq.nii.ac.jp:02002710","sets":["1164:5352:1740054670081:1749434252473"]},"path":["1749434252473"],"owner":"80578","recid":"2002710","title":["テンソル分解を用いたX染色体不活性化関連遺伝子の同定"],"pubdate":{"attribute_name":"PubDate","attribute_value":"2025-06-14"},"_buckets":{"deposit":"d7a49bba-266b-4396-97ae-c4250bb2067c"},"_deposit":{"id":"2002710","pid":{"type":"depid","value":"2002710","revision_id":0},"owners":[80578],"status":"published","created_by":80578},"item_title":"テンソル分解を用いたX染色体不活性化関連遺伝子の同定","author_link":[],"item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"テンソル分解を用いたX染色体不活性化関連遺伝子の同定","subitem_title_language":"ja"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"バイオ情報学(IPSJ-BIO)1","subitem_subject_scheme":"Other"}]},"item_type_id":"4","publish_date":"2025-06-14","item_4_text_3":{"attribute_name":"著者所属","attribute_value_mlt":[{"subitem_text_value":"中央大学"},{"subitem_text_value":"中央大学"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_publisher":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"情報処理学会","subitem_publisher_language":"ja"}]},"publish_status":"0","weko_shared_id":-1,"item_file_price":{"attribute_name":"Billing file","attribute_type":"file","attribute_value_mlt":[{"url":{"url":"https://ipsj.ixsq.nii.ac.jp/record/2002710/files/IPSJ-BIO25082034.pdf","label":"IPSJ-BIO25082034.pdf"},"date":[{"dateType":"Available","dateValue":"2027-06-14"}],"format":"application/pdf","billing":["billing_file"],"filename":"IPSJ-BIO25082034.pdf","filesize":[{"value":"1.4 MB"}],"mimetype":"application/pdf","priceinfo":[{"tax":["include_tax"],"price":"660","billingrole":"5"},{"tax":["include_tax"],"price":"330","billingrole":"6"},{"tax":["include_tax"],"price":"0","billingrole":"41"},{"tax":["include_tax"],"price":"0","billingrole":"44"}],"accessrole":"open_date","version_id":"4ff9d369-f417-418d-a98e-d8f856e09e59","displaytype":"detail","licensetype":"license_note","license_note":"Copyright (c) 2025 by the Information Processing Society of Japan"}]},"item_4_creator_5":{"attribute_name":"著者名","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"大川,真亜知"}]},{"creatorNames":[{"creatorName":"田口,善弘"}]}]},"item_4_source_id_9":{"attribute_name":"書誌レコードID","attribute_value_mlt":[{"subitem_source_identifier":"AA12055912","subitem_source_identifier_type":"NCID"}]},"item_4_textarea_12":{"attribute_name":"Notice","attribute_value_mlt":[{"subitem_textarea_value":"SIG Technical Reports are nonrefereed and hence may later appear in any journals, conferences, symposia, etc."}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourceuri":"http://purl.org/coar/resource_type/c_18gh","resourcetype":"technical report"}]},"item_4_source_id_11":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"2188-8590","subitem_source_identifier_type":"ISSN"}]},"item_4_description_7":{"attribute_name":"論文抄録","attribute_value_mlt":[{"subitem_description":"本研究では、X染色体不活性化(XCI)の偏りに関連する新規遺伝子の同定を目的とした。既知のXCI状態を持つ検証コホートと、未診断の希少疾患患者からなる応用コホートの遺伝子発現データを用い、4階のテンソルを構築後、TDbasedUFE法を適用して解析を行った。解析の結果、XCIの偏りと有意に関連する複数の遺伝子が抽出された。さらに、GOエンリッチメント解析により、RNAプロセシングや翻訳制御、免疫応答に関連する機能が強調された。これらの結果は、XCIがリボソーム機能やRNA代謝のみならず、免疫機構にも影響を及ぼす可能性を示唆している。","subitem_description_type":"Other"}]},"item_4_biblio_info_10":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicPageEnd":"6","bibliographic_titles":[{"bibliographic_title":"研究報告バイオ情報学(BIO)"}],"bibliographicPageStart":"1","bibliographicIssueDates":{"bibliographicIssueDate":"2025-06-14","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"34","bibliographicVolumeNumber":"2025-BIO-82"}]},"relation_version_is_last":true,"weko_creator_id":"80578"},"created":"2025-06-09T02:38:17.480872+00:00","updated":"2025-10-09T02:37:07.646529+00:00"}