{"created":"2025-01-19T01:02:05.493013+00:00","metadata":{"_oai":{"id":"oai:ipsj.ixsq.nii.ac.jp:00197656","sets":["1164:5352:9740:9828"]},"path":["9828"],"owner":"44499","recid":"197656","title":["配列類似性ネットワークに基づく高感度な遠縁タンパク質検索"],"pubdate":{"attribute_name":"公開日","attribute_value":"2019-06-10"},"_buckets":{"deposit":"5b979691-2481-4a01-a4e8-786fe97d54a1"},"_deposit":{"id":"197656","pid":{"type":"depid","value":"197656","revision_id":0},"owners":[44499],"status":"published","created_by":44499},"item_title":"配列類似性ネットワークに基づく高感度な遠縁タンパク質検索","author_link":["474700","474701"],"item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"配列類似性ネットワークに基づく高感度な遠縁タンパク質検索"}]},"item_type_id":"4","publish_date":"2019-06-10","item_4_text_3":{"attribute_name":"著者所属","attribute_value_mlt":[{"subitem_text_value":"School of Computing, Tokyo Institute of Technology"},{"subitem_text_value":"School of Computing, Tokyo Institute of Technology"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_publisher":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"情報処理学会","subitem_publisher_language":"ja"}]},"publish_status":"0","weko_shared_id":-1,"item_file_price":{"attribute_name":"Billing file","attribute_type":"file","attribute_value_mlt":[{"url":{"url":"https://ipsj.ixsq.nii.ac.jp/record/197656/files/IPSJ-BIO19058056.pdf","label":"IPSJ-BIO19058056.pdf"},"date":[{"dateType":"Available","dateValue":"2021-06-10"}],"format":"application/pdf","billing":["billing_file"],"filename":"IPSJ-BIO19058056.pdf","filesize":[{"value":"779.1 kB"}],"mimetype":"application/pdf","priceinfo":[{"tax":["include_tax"],"price":"660","billingrole":"5"},{"tax":["include_tax"],"price":"330","billingrole":"6"},{"tax":["include_tax"],"price":"0","billingrole":"41"},{"tax":["include_tax"],"price":"0","billingrole":"44"}],"accessrole":"open_date","version_id":"5719878a-5115-4426-857e-c0a9e6530d58","displaytype":"detail","licensetype":"license_note","license_note":"Copyright (c) 2019 by the Information Processing Society of Japan"}]},"item_4_creator_5":{"attribute_name":"著者名","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"牧垣, 秀一朗"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"石田, 貴士"}],"nameIdentifiers":[{}]}]},"item_4_source_id_9":{"attribute_name":"書誌レコードID","attribute_value_mlt":[{"subitem_source_identifier":"AA12055912","subitem_source_identifier_type":"NCID"}]},"item_4_textarea_12":{"attribute_name":"Notice","attribute_value_mlt":[{"subitem_textarea_value":"SIG Technical Reports are nonrefereed and hence may later appear in any journals, conferences, symposia, etc."}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourceuri":"http://purl.org/coar/resource_type/c_18gh","resourcetype":"technical report"}]},"item_4_source_id_11":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"2188-8590","subitem_source_identifier_type":"ISSN"}]},"item_4_description_7":{"attribute_name":"論文抄録","attribute_value_mlt":[{"subitem_description":"相同タンパク質検索は，その構造や機能の予測・進化の解明に重要であり，タンパク質構造・機能研究の中心技術となっている．そのなかで，配列類似度は低いが構造や機能は類似しているタンパク質が多く存在していることが知られるようになり，そのような遠縁のタンパク質をデータベース中から発見する研究が進められている．本研究では，アミノ酸配列データベース内に配列類似性に基づくネットワーク構造を定義し，そのネットワークを検索することで，遠縁のタンパク質を高感度に検出することを試みた．ネットワーク構造を定義することにより，進化の関係を検索に導入することができ，共通の祖先を経由した遠縁のタンパク質を発見できると考えられる．また，アミノ酸配列データベースとタンパク質立体構造データベースを本手法で結合することにより，アミノ酸配列から遠縁の構造既知のタンパク質を発見することも期待できる．","subitem_description_type":"Other"}]},"item_4_biblio_info_10":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicPageEnd":"3","bibliographic_titles":[{"bibliographic_title":"研究報告バイオ情報学（BIO）"}],"bibliographicPageStart":"1","bibliographicIssueDates":{"bibliographicIssueDate":"2019-06-10","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"56","bibliographicVolumeNumber":"2019-BIO-58"}]},"relation_version_is_last":true,"weko_creator_id":"44499"},"id":197656,"updated":"2025-01-19T22:15:53.260921+00:00","links":{}}