{"created":"2025-01-19T00:19:54.133983+00:00","updated":"2025-01-20T18:59:45.773493+00:00","metadata":{"_oai":{"id":"oai:ipsj.ixsq.nii.ac.jp:00142451","sets":["1164:2735:7896:8280"]},"path":["8280"],"owner":"11","recid":"142451","title":["軸索伸長の抑制因子と因子阻害剤の浸透率の推定"],"pubdate":{"attribute_name":"公開日","attribute_value":"2015-06-16"},"_buckets":{"deposit":"762655c3-6128-4832-893f-d01c9bf64cdb"},"_deposit":{"id":"142451","pid":{"type":"depid","value":"142451","revision_id":0},"owners":[11],"status":"published","created_by":11},"item_title":"軸索伸長の抑制因子と因子阻害剤の浸透率の推定","author_link":["211417","211413","211412","211415","211419","211416","211418","211414"],"item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"軸索伸長の抑制因子と因子阻害剤の浸透率の推定"},{"subitem_title":"Estimations of Axonal Growth Inhibitor and Reagent Permeability","subitem_title_language":"en"}]},"item_type_id":"4","publish_date":"2015-06-16","item_4_text_3":{"attribute_name":"著者所属","attribute_value_mlt":[{"subitem_text_value":"愛知県立大学大学院情報科研究科"},{"subitem_text_value":"奈良先端科学技術大学院大学情報科学研究科"},{"subitem_text_value":"奈良先端科学技術大学院大学情報科学研究科"},{"subitem_text_value":"愛知県立大学大学院情報科研究科"}]},"item_4_text_4":{"attribute_name":"著者所属(英)","attribute_value_mlt":[{"subitem_text_value":"School of Information Science and Technology, Aichi Prefectural University","subitem_text_language":"en"},{"subitem_text_value":"Graduate School of Information Science, Nara Institute of Science and Technology","subitem_text_language":"en"},{"subitem_text_value":"Graduate School of Information Science, Nara Institute of Science and Technology","subitem_text_language":"en"},{"subitem_text_value":"School of Information Science and Technology, Aichi Prefectural University","subitem_text_language":"en"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_publisher":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"情報処理学会","subitem_publisher_language":"ja"}]},"publish_status":"0","weko_shared_id":-1,"item_file_price":{"attribute_name":"Billing file","attribute_type":"file","attribute_value_mlt":[{"url":{"url":"https://ipsj.ixsq.nii.ac.jp/record/142451/files/IPSJ-MPS15103050.pdf"},"date":[{"dateType":"Available","dateValue":"2100-01-01"}],"format":"application/pdf","billing":["billing_file"],"filename":"IPSJ-MPS15103050.pdf","filesize":[{"value":"359.2 kB"}],"mimetype":"application/pdf","priceinfo":[{"tax":["include_tax"],"price":"0","billingrole":"17"},{"tax":["include_tax"],"price":"0","billingrole":"44"}],"accessrole":"open_date","version_id":"7bd79366-9944-4b13-a006-732c3c8c43ad","displaytype":"detail","licensetype":"license_note","license_note":"Copyright (c) 2015 by the Institute of Electronics, Information and Communication Engineers This SIG report is only available to those in membership of the SIG."}]},"item_4_creator_5":{"attribute_name":"著者名","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"柿崎, 遼"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"丸野, 由希"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"池田, 和司"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"作村, 諭一"}],"nameIdentifiers":[{}]}]},"item_4_creator_6":{"attribute_name":"著者名(英)","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"Haruka, Kakizaki","creatorNameLang":"en"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Yuki, Maruno","creatorNameLang":"en"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Kazushi, Ikeda","creatorNameLang":"en"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Yuichi, Sakumura","creatorNameLang":"en"}],"nameIdentifiers":[{}]}]},"item_4_source_id_9":{"attribute_name":"書誌レコードID","attribute_value_mlt":[{"subitem_source_identifier":"AN10505667","subitem_source_identifier_type":"NCID"}]},"item_4_textarea_12":{"attribute_name":"Notice","attribute_value_mlt":[{"subitem_textarea_value":"SIG Technical Reports are nonrefereed and hence may later appear in any journals, conferences, symposia, etc."}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourceuri":"http://purl.org/coar/resource_type/c_18gh","resourcetype":"technical report"}]},"item_4_source_id_11":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"2188-8833","subitem_source_identifier_type":"ISSN"}]},"item_4_description_7":{"attribute_name":"論文抄録","attribute_value_mlt":[{"subitem_description":"神経軸索の伸長過程は多種多様な分子群の生化学反応の連鎖によって実現される．化学的な薬剤を用いて伸長を抑える分子を阻害すれば軸索を伸長させることができ，再生医療のための薬剤開発が見込まれる．しかし，最適な分子阻害パターンと，それぞれの阻害剤の浸透率の違いによる実効的な効き具合は不明である．本研究では，先行研究に浸透率モデルを導入し，分子阻害パターンと浸透率の推定を行う．","subitem_description_type":"Other"}]},"item_4_description_8":{"attribute_name":"論文抄録(英)","attribute_value_mlt":[{"subitem_description":"Neuronal axonal growth is regulated by biochemical reactions of various molecules. It is possible to elongate axon by applying the chemical compound that suppresses activities of axonal growth-inhibiting molecules. To develop a novel compound for regenerative medicine, we need to know molecules to be suppressed, their suppression levels, and the effective permeability of the compound in vivo. In this work, we propose the algorithm by which suppression pattern effective for axonal growth and compound permeability can be estimated from the dataset of existing compounds.","subitem_description_type":"Other"}]},"item_4_biblio_info_10":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicPageEnd":"4","bibliographic_titles":[{"bibliographic_title":"研究報告数理モデル化と問題解決（MPS）"}],"bibliographicPageStart":"1","bibliographicIssueDates":{"bibliographicIssueDate":"2015-06-16","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"50","bibliographicVolumeNumber":"2015-MPS-103"}]},"relation_version_is_last":true,"weko_creator_id":"11"},"id":142451,"links":{}}