A Method to Support Cell Physiological Modelling Using Description Language and Ontology

• Item type: Trans(1)
• 公開日: 2006-11-15
• タイトル: A Method to Support Cell Physiological Modelling Using Description Language and Ontology
• タイトル / 言語: en
• タイトル: A Method to Support Cell Physiological Modelling Using Description Language and Ontology
• 言語: eng
• キーワード / 主題Scheme: Other
• キーワード / 主題: Original Papers
• 資源タイプ / 資源タイプ識別子: http://purl.org/coar/resource_type/c_6501
• 資源タイプ: journal article
• 著者所属: ASTEM Research Institute of Kyoto
• 著者所属: Graduate School of Informatics Kyoto University
• 著者所属: Graduate School of Informatics Kyoto University
• 著者所属: Academic Center for Computing and Media Studies Kyoto University
• 著者所属: Graduate School of Informatics Kyoto University
• 著者所属: Academic Center for Computing and Media Studies Kyoto University
• 著者所属(英): en
• 著者所属(英): ASTEM Research Institute of Kyoto
• 著者所属(英): en
• 著者所属(英): Graduate School of Informatics, Kyoto University
• 著者所属(英): en
• 著者所属(英): Graduate School of Informatics, Kyoto University
• 著者所属(英): en
• 著者所属(英): Academic Center for Computing and Media Studies, Kyoto University
• 著者所属(英): en
• 著者所属(英): Graduate School of Informatics, Kyoto University
• 著者所属(英): en
• 著者所属(英): Academic Center for Computing and Media Studies, Kyoto University
• 著者名: Takao, Shimayoshi; Kazuhiro, Komurasaki; Akira, Amano; Takeshi, Iwashita; Tetsuya, Matsuda; Masanori, Kanazawa
• 著者名(英): Takao, Shimayoshi; Kazuhiro, Komurasaki; Akira, Amano; Takeshi, Iwashita; Tetsuya, Matsuda; Masanori, Kanazawa
• 論文抄録 / 内容記述タイプ: Other
• 論文抄録 / 内容記述: The development of physiological cell models to support the understanding of biological mechanisms gains increasingly importance. Due to the complexity of biological systems whole cell models which are composed of many imported component models of functional elements get quite complex making modifications difficult. Here we propose a method to enhance structural changes of cell models employing the markup languages of CellML and our original PMSML (Physiological Model Structure Markup Language) in addition to a new ontology for cell physiological modelling the Cell Model Ontology. In particular a method to make references from CellML files to the ontology and a method to assist with manipulation of model structures using PMSML together with the Cell Model Ontology are reported. Using these methods two software utilities an interactive ontology ID assigner the CellML Ontologizer and a graphical cell model editor the Cell Structure Editor are implemented. Experimental results proved that the proposed method and the implemented software are useful for the modification of physiological models.
• 論文抄録(英) / 内容記述タイプ: Other
• 論文抄録(英) / 内容記述: The development of physiological cell models to support the understanding of biological mechanisms gains increasingly importance. Due to the complexity of biological systems, whole cell models, which are composed of many imported component models of functional elements, get quite complex, making modifications difficult. Here, we propose a method to enhance structural changes of cell models, employing the markup languages of CellML and our original PMSML (Physiological Model Structure Markup Language), in addition to a new ontology for cell physiological modelling, the Cell Model Ontology. In particular, a method to make references from CellML files to the ontology and a method to assist with manipulation of model structures using PMSML together with the Cell Model Ontology are reported. Using these methods two software utilities, an interactive ontology ID assigner, the CellML Ontologizer, and a graphical cell model editor, the Cell Structure Editor, are implemented. Experimental results proved that the proposed method and the implemented software are useful for the modification of physiological models.
• 書誌レコードID / 収録物識別子タイプ: NCID
• 書誌レコードID / 収録物識別子: AA12177013
• 書誌情報: IPSJ Transactions on Bioinformatics （TBIO）; 巻 47, 号 SIG17(TBIO1), p. 83-92, 発行日 2006-11-15
• ISSN / 収録物識別子タイプ: ISSN
• ISSN / 収録物識別子: 1882-6679
• 出版者 / 言語: ja
• 出版者: 情報処理学会